Hard capsules
Hard capsules are a common pharmaceutical and supplement dosage form characterised by their two-piece cylindrical structure. These capsules consist of two pre-formed sections: a shorter, wider “cap” and a longer, narrower “body.” The cap is designed with a slightly larger diameter, allowing it to slip snugly over the body. This precise fit creates a secure, hermetically sealed enclosure, effectively protecting the encapsulated contents from external factors like moisture and air. This design ensures drug stability and facilitates accurate and convenient oral administration.
Vitalife Biotech HARD CAPSULES OEM service
hard capsules OEM manufacturer
Hard capsules are among the most versatile oral dosage forms.
They support a wide range of goals, from protecting active substances in the stomach to meeting dietary preferences. Whether enteric-coated capsules shield the stomach or vegetarian capsules, there’s a capsule to suit every need.
As the biggest hard capsule manufacturer in China, we have 20+ fully automatic hard capsule production lines, which can produce veggie capsules, enteric capsules, sustained-release capsules, gastric capsules, microencapsulation capsules, gelatin capsules, transparent capsules, and pearlescent capsules.
Vitalife Biotech Hard Capsule Manufacturing Process
| Specification | 00# | 0# | 1# | 2# | 3# | 4# |
| Length | 23.2mm | 21.7mm | 19.5mm | 17.8mm | 15.8mm | 14.3mm |
| Diameter | 7.77mm | 7.71mm | 6.97mm | 6.42mm | 5.9mm | 5.39mm |
| Volume | 0.79ml | 0.67ml | 0.5ml | 0.37ml | 0.3ml | 0.21ml |
| Approx. Filling Capacity | 0.8g | 0.5g | 0.35g | 0.25g | 0.2g | 0.13g |
Existing moulds for regular models
| Model | Capacity | Daily Capacity |
| 00# hard capsule | 250-500mg | 900,000 caps |
| 00# hard capsule | 300-600mg | 900,000 caps |
| 00# hard capsule | 750-950mg | 2,400,000 caps |
| 0# hard capsule | 500mg | 3,000,000 caps |
| 1# hard capsule | 300mg | 1,500,000 caps |
| 2# hard capsule | 150-200mg | 3,000,000 caps |
Bottle Packaging
Bottling stands as a prevalent method in capsule packaging. This process involves placing capsules into either plastic or glass bottles, followed by sealing with a tamper-evident cap. A desiccant is frequently included within the bottle to maintain a dry environment, ensuring the integrity and stability of the capsules. This approach is widely adopted due to its simplicity, cost-effectiveness, and suitability for various capsule formulations.
Blister Packaging
Blister packs are a prevalent packaging solution in the pharmaceutical industry, offering enhanced product protection and ease of use for solid-dosage medications such as tablets and capsules. Among the various types of blister packs, PTP Foil (Alu-PVC) and Cold Form Foil (Alu-Alu) are two common options, each distinguished by its unique structure, performance characteristics, and application suitability.
The selection between PTP Foil and Cold Form Foil blister packs hinges on a balance between cost considerations and the specific protection requirements of the drug product. PTP Foil blisters offer an economical solution for medications with moderate sensitivity, while Cold Form Foil blisters provide a robust barrier for moisture-sensitive and oxygen-sensitive pharmaceuticals, ensuring drug product integrity and shelf-life stability.
Alu-PVC Blister – 10 caps/blister
Alu-PVC Blister – 12 caps/blister
Alu-Alu Blister – 10 caps/blister
Comparison of Alu-PVC and Alu-Alu
| Packaging Material | Alu-PVC | Alu-Alu |
| Cost | Low | High |
| Forming method | Thermoforming | Cold forming |
| Application | General-purpose drugs | light-sensitive drugs moisture-sensitive drugs |
| Barrier properties | General oxygen-barrier, moisture-barrier | Excellent completely oxygen-barrier, moisture-barrier & light-shielding |
| Visibility | Visible (transparent PVC) | Invisible |
